![GeneAb™ Arginase-1 [IHC118] on Liver](/images/product/original/Arginase-1-IHC118-Liver-Cancer.jpg)
GeneAb™ Arginase-1 [IHC118] on Liver
Arginase-1, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly in hepatocytes. Arginase-1 plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithine and urea. Argininemia is an inherited autosomal recessive disorder characterized by a buildup of arginine and ammonia in the blood. Anti-Arginase-1 is highly specific for hepatocytes, and is therefore a sensitive and specific marker of benign and malignant hepatic tumours.
CLONE:
IHC118
ISOTYPE:
IgG2b
HOST SPECIES:
Rabbit
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Liver
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVDR