![GeneAb™ Beta-Catenin [IHC516] on Colon Cancer](/images/product/original/Beta-Catenin-IHC516-Colon-Cancer.jpg)
GeneAb™ Beta-Catenin [IHC516] on Colon Cancer
β-Catenin is a cytoplasmic protein with a dual role in cell-cell adhesion and gene expression. It is normally present in the submembranous regions of the cell, and nuclear accumulation of β-Catenin has been found to occur as a result of gene mutations. This accumulation is useful in identifying desmoid tumours (fibromatosis) in the abdomen and breast, and is therefore useful in differentiating other cell neoplasms in these regions.
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CLONE:
IHC516
ISOTYPE:
IgG1
HOST SPECIES:
Mouse
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Fibromatosis of Breast
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVDR