β-Catenin is a cytoplasmic protein with a dual role in cell-cell adhesion and gene expression. It is normally present in the submembranous regions of the cell, and nuclear accumulation of β-Catenin has been found to occur as a result of gene mutations. This accumulation is useful in identifying desmoid tumours (fibromatosis) in the abdomen and breast, and is therefore useful in differentiating other cell neoplasms in these regions.

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• MSDS

CLONE:
IHC516

ISOTYPE:
IgG1

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Fibromatosis of Breast

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR