COX-2, also known as Cyclooxygenase 2, catalyzes the conversion of arachidonic acid to prostaglandin H2. The inhibition of COX-2 using non-steroidal anti-inflammatory agents limits angiogenesis and tumour growth, and increases apoptosis. The overexpression of COX-2 is linked to increased microvascular density.
CLONE:
IHC081
ISOTYPE:
HOST SPECIES:
Rabbit
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Intestine Cancer, Colon Adenocarcinoma
DILUTION RANGE:
INTENDED USE/REG. STATUS:
RUO