Cytokeratin 8 & 18 are present in various epithelia including that of the breast, thyroid, respiratory tract, and gastrointestinal tract. Anti-Cytokeratin 8 & 18 stains adenocarcinomas and most non-keratinizing squamous carcinomas, but does not stain keratinizing squamous carcinomas. Since Cytokeratin 18 is scarce in normal epidermis, Anti-Cytokeratin 8 & 18 is used to detect Paget cells in such samples. Cytokeratin 8 & 18 helps identify colorectal carcinoma metastases as it is more sensitive than genetic tests.

• IHC559-Cytokeratin 8 18 Datasheet-RUO

• MSDS

CLONE:
IHC559

ISOTYPE:
Rabbit IgG/Mouse IgG1

HOST SPECIES:
Rabbit/Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Breast Ductal Carcinoma, Colon Cancer

DILUTION RANGE:


INTENDED USE/REG. STATUS:
RUO