GeneAb™ HER2/neu [IHC042] on Breast
The HER2/neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number of carcinomas. Overexpression of the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between HER2 and p53 has also been documented, as overexpression of both proteins has been associated with early invasion and metastasis in bladder cancer.
CLONE:
IHC042
ISOTYPE:
IgG2a
HOST SPECIES:
Mouse
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Breast Carcinoma
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVD
ADDITIONAL INFORMATION:
NordiQC Rating: Optimal
(Assessment Run B31 2021)